Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 12 de 12
Filter
1.
Rev.chil.ortop.traumatol. ; 63(2): 83-86, ago.2022. ilus, graf
Article in Spanish | LILACS | ID: biblio-1436080

ABSTRACT

OBJETIVO Determinar la resistencia máxima a la tracción (RMT) de la continuación prepatelar del cuádriceps (CPC).MATERIALES Y MÉTODOS Se realizó un estudio en cadáveres humanos. Fueron incluidos diez especímenes, en los cuales se utilizaron los tercios proximal y medial de la cortical anterior de la patela para evaluar las propiedades mecánicas de la CPC. En cada espécimen, se estudió un área de sección transversal de 0,2 cm2 (A1) y 1 cm2 (A2). Se aplicó una carga gradual para determinar la RMT.RESULTADOS La mediana de la RMT en el A1 fue de 232,56 N (rango: 141,23 N a 295,33 N) y en el A2 fue de 335,30 N (rango: 216,45 N a 371,40 N). El incremento en la TMR fue significativo entre las 2 áreas (p = 0,006).CONCLUSIÓN El ignificado clínico de este estudio es que la CPC es un tejido fuerte que puede servir de anclaje seguro para reconstrucciones alrededor de la patela. Un área relativamente pequeña tolera al menos 140 N y, a medida que crece el área, también aumenta la RMT.


OBJETIVE To determine the ultimate tensile strength (UTS) of the prepatellar quadriceps continuation (PQC). MATERIALS AND METHODS A human cadaveric study was performed. Ten fresh-frozen specimens were used. The proximal and medial thirds of the anterior cortex of the patella were used to assess the mechanical properties of the PQC. In each specimen, transverse section areas measuring 0.2 cm2 (A1) and 1 cm2 (A2) were studied. A gradual load was applied to determine the UTS. RESULTS The median UTS of A1 was of 232.56 N (range: 141.23 N to 295.33 N), and that of A2 was of 335.30 N (range: 216.45 N to 371.40 N). The increment in UTS was significant between the 2 areas (p » 0.006). CONCLUSION The clinical significance of the present study lies in the fact that it shows that the PQC is a strong tissue that can be a safe anchor for reconstruction around the patella. A relatively small area supports at least 140 N, and, as the area grows, the UTS increases as well.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Tensile Strength , Quadriceps Muscle/physiopathology , Biomechanical Phenomena , Knee Joint/physiopathology
2.
Clinics ; 75: e1768, 2020. tab, graf
Article in English | LILACS | ID: biblio-1133466

ABSTRACT

OBJECTIVES: Menopause marks the end of women's reproductive period and can lead to sarcopenia and osteoporosis (OP), increasing the risk of falls and fractures. The aim of this study is to evaluate the influence of normal and low bone mineral density (BMD) on muscular activity, observed through inflammatory edema when mapping using magnetic resonance imaging (MRI) on the quadriceps muscle of postmenopausal women. METHODS: This was a cross-sectional study involving 16 older women, who were divided into two groups: osteoporosis group (OG), older women with OP, and control group (CG), older women without OP. The groups were evaluated in terms of nuclear MRI exam before and after carrying out fatigue protocol exercises using an isokinetic dynamometer and squatting exercises. RESULTS: The results of the present study showed that in intragroup comparisons, for both groups, there was a significant increase (p<0.05) in the T2 signal of the nuclear MRI in the quadriceps muscle after carrying out exercises using both thighs. In the intergroup comparison, no statistically significant difference was observed between the OG and CG, pre- (p=0.343) and postexercise (p=0.874). CONCLUSION: The acute muscular activation of the quadriceps evaluated by T2 mapping on nuclear MRI equipment is equal in women with and without OP in the postmenopausal phase. BMD did not interfere with muscle response to exercise when muscle fatigue was reached.


Subject(s)
Humans , Female , Aged , Magnetic Resonance Imaging/methods , Postmenopause , Quadriceps Muscle/diagnostic imaging , Absorptiometry, Photon , Bone Density , Osteoporosis, Postmenopausal , Cross-Sectional Studies , Quadriceps Muscle/physiopathology
3.
Braz. j. med. biol. res ; 53(4): e8770, 2020. tab, graf
Article in English | LILACS | ID: biblio-1089354

ABSTRACT

Early mobilization is beneficial for critically ill patients because it reduces muscle weakness acquired in intensive care units. The objective of this study was to assess the effect of functional electrical stimulation (FES) and passive cycle ergometry (PCE) on the nitrous stress and inflammatory cytometry in critically ill patients. This was a controlled, randomized, open clinical trial carried out in a 16-bed intensive care unit. The patients were randomized into four groups: Control group (n=10), did not undergo any therapeutic intervention during the study; PCE group (n=9), lower-limb PCE for 30 cycles/min for 20 min; FES group (n=9), electrical stimulation of quadriceps muscle for 20 min; and FES with PCE group (n=7), patients underwent PCE and FES, with their order determined randomly. The serum levels of nitric oxide, tumor necrosis factor alpha, interferon gamma, and interleukins 6 and 10 were analyzed before and after the intervention. There were no differences in clinical or demographic characteristics between the groups. The results revealed reduced nitric oxide concentrations one hour after using PCE (P<0.001) and FES (P<0.05), thereby indicating that these therapies may reduce cellular nitrosative stress when applied separately. Tumor necrosis factor alpha levels were reduced after the PCE intervention (P=0.049). PCE and FES reduced nitric oxide levels, demonstrating beneficial effects on the reduction of nitrosative stress. PCE was the only treatment that reduced the tumor necrosis factor alpha concentration.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Respiration, Artificial/methods , Motion Therapy, Continuous Passive/methods , Cytokines/blood , Critical Illness/therapy , Nitrosative Stress/physiology , Biomarkers/blood , Critical Illness/rehabilitation , Oxidative Stress/physiology , Electric Stimulation/methods , Quadriceps Muscle/physiopathology , Inflammation/immunology , Inflammation/metabolism , Intensive Care Units
4.
Rev. Assoc. Med. Bras. (1992) ; 65(7): 952-958, July 2019. tab, graf
Article in English | LILACS | ID: biblio-1013011

ABSTRACT

SUMMARY PURPOSE In this prospective observational study, we aimed to investigate the role of the maximum compressed (MC) and uncompressed (UC) thickness of the quadriceps femoris muscle (QFMT) measured by ultrasonography (USG) in the detection of nutritional risk in intensive care patients (ICPs) with different volume status. METHODS 55 patients were included. Right, left, and total ucQFMT and mcQFMT measurements were obtained by a standard USG device within the first 48 hours after ICU admission. Clinical examination and the USG device were used to determine the volume status of the patients. SOFA, APACHE II, modified NUTRIC scores, and demographic data were collected. RESULTS There was a significant difference between the nutritional risk of patients in terms of left, right, and total mcQFMT measurements (p=0.025, p=0.039; p=0.028, respectively), mechanical ventilation requirement (p=0.014), presence of infection (p=0.019), and sepsis (p=0.006). There was no significant difference between different volume statuses in terms of mcQFMT measurements. In the multi-variance analysis, mcQFMT measurements were found to be independently associated with high nutritional risk (p=0.019, Exp(B)=0.256, 95%CI=0.082-0.800 for modified NUTRIC score ≥ 5), and higher nutritional risk (p=0.009, Exp(B)=0.144, 95%CI=0.033-0.620 for modified NUTRIC score ≥ 6). a Total mcQFMT value below 1.36 cm was a predictor for higher nutritional risk with 79% sensitivity and 70% specificity (AUC=0.749, p=0.002, likelihood ratio=2.04). CONCLUSION Ultrasonographic measurement of total mcQFMT can be used as a novel nutritional risk assessment parameter in medical ICPs with different volume statuses. Thus, patients who could benefit from aggressive nutritional therapy can be easily identified in these patient groups.


RESUMO OBJETIVO Neste estudo observacional prospectivo, objetivamos investigar o papel da espessura do músculo quadríceps femoral (QFMT) comprimido (mc) e não comprimido (uc) medida pela ultrassonografia (USG) na detecção do risco nutricional em pacientes de terapia intensiva (ICPs) com status de volume diferente. MÉTODOS Cinquenta e cinco pacientes foram incluídos. As medidas direita, esquerda e total de ucQFMT e mcQFMT foram obtidas por um dispositivo USG padrão nas primeiras 48 horas após a admissão na UTI. O exame clínico e o dispositivo USG foram usados para determinar o status volumétrico dos pacientes. Sofa, Apache II, escores Nutric modificados e dados demográficos foram coletados. RESULTADOS Houve diferença significativa entre o risco nutricional dos pacientes em termos de medidas da QTFMT esquerda, direita e total (p=0,025, p=0,039; p=0,028, respectivamente), necessidade de ventilação mecânica (p=0,014), presença de infecção (p=0,019) e sepse (p=0,006). Não houve diferença significativa entre os diferentes status de volume em termos de medidas de mcQFMT. Na análise de variância múltipla, verificou-se que as medidas da FCFMT estavam independentemente associadas a alto risco nutricional (p=0,019, Exp (B)=0,256, 95%CI=0,082-0,800 para escore Nutric modificado ≥ 5) e maior risco nutricional (p=0,009, Exp (B)=0,144, 95%CI=0,033-0,620 para o escore Nutric modificado ≥ 6). O valor total de mcQFMT abaixo de 1,36 cm foi um preditor de maior risco nutricional com sensibilidade de 79% e especificidade de 70% (ASC=0,749, p=0,002, razão de verossimilhança = 2,04). CONCLUSÃO A medida ultrassonográfica do mcQFMT total pode ser usada como um novo parâmetro de avaliação de risco nutricional em ICPs médicas com diferentes status de volume. Assim, pacientes que podem se beneficiar de uma terapia nutricional agressiva podem ser facilmente identificados nesses grupos de pacientes.


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Nutritional Status/physiology , Ultrasonography/methods , Quadriceps Muscle/pathology , Quadriceps Muscle/diagnostic imaging , Reference Values , Respiration, Artificial/adverse effects , Logistic Models , Nutrition Assessment , Prospective Studies , Sensitivity and Specificity , Critical Illness , Risk Assessment , APACHE , Malnutrition/physiopathology , Malnutrition/pathology , Malnutrition/diagnostic imaging , Nutrition Therapy/methods , Quadriceps Muscle/physiopathology , Intensive Care Units , Length of Stay , Middle Aged
5.
Rev. bras. ter. intensiva ; 29(4): 476-480, out.-dez. 2017. tab, graf
Article in Portuguese | LILACS | ID: biblio-899543

ABSTRACT

RESUMO Objetivo: Avaliar a intra e interconfiabilidade, e a facilidade de medir a espessura muscular do quadríceps, usando ultrassom à beira do leito. Métodos: Trata-se de um estudo prospectivo, observacional. A avaliação da espessura muscular do quadríceps foi realizada em dois pontos de referência e quantificada com ultrassom portátil em modo B em dois voluntários saudáveis. Para padronização das medidas e validação das coletas das imagens, foi realizada capacitação da equipe por meio de treinamentos com aulas teóricas e práticas, com carga horária de 6 horas. Resultados: Foram examinadas 112 imagens pelo treinador e comparadas com os alunos. A correlação de Person encontrou excelente relação entre o treinador e todos os alunos (R2 > 0,90). A melhor associação foi entre o treinador e os nutricionistas (R2: 0,99; p < 0,001), e a pior, entre o treinador e alunos médicos (R2: 0,92; p < 0,001). Quanto à comparação de Bland-Altman, a maior porcentagem de erro encontrada entre treinador e alunos foi de 5,12% (IC95% 3,64 - 12,37) e a menor, 1,01% (IC95% 0,72 - 2,58); o maior viés dos valores descrito foi -0,12 ± 0,19, e o menor, -0,01 ± 0,04. Conclusão: Os dados analisados mostraram boa correlação entre as medidas feitas pelo instrutor e alunos, mostrando que o ultrassom de músculo quadríceps é uma ferramenta viável e de fácil aplicabilidade.


ABSTRACT Objective: To evaluate the intra- and inter-reliability and the ease of measuring the quadriceps muscle thickness using bedside ultrasound. Methods: This is a prospective, observational study. The assessment of quadriceps muscle thickness was performed at two reference points and was quantified using portable B-mode ultrasound in two healthy volunteers. For standardization of measurements and validation of image collections, the team was trained through theoretical and practical classes, with a 6-hour workload. Results: A total of 112 images were examined by the coach and compared with the trainees. Pearson's correlation analysis found an excellent relationship between the coach and all trainees (R2 > 0.90). The best association was between the coach and the dietitians (R2: 0.99; p < 0.001), and the worst association was between the coach and the medical trainees (R2: 0.92; p < 0.001). In the Bland-Altman comparison, the highest error rate found between coach and trainees was 5.12% (95% confidence interval [CI] 3.64-12.37), and the lowest was 1.01% (95%CI 0.72 - 2.58); the highest bias of the values described was -0.12 ± 0.19, and the lowest was -0.01 ± 0.04. Conclusion: The data analyzed showed a good correlation between the measurements made by the coach and trainees, indicating that ultrasound of the quadriceps muscle is a viable and easily applicable tool.


Subject(s)
Humans , Male , Female , Adult , Ultrasonography/methods , Point-of-Care Systems , Quadriceps Muscle/diagnostic imaging , Prospective Studies , Reproducibility of Results , Quadriceps Muscle/physiopathology , Middle Aged
7.
J. bras. pneumol ; 41(4): 305-312, July-Aug. 2015. tab, ilus
Article in English | LILACS | ID: lil-759335

ABSTRACT

AbstractObjective: To compare equations for predicting peak quadriceps femoris (QF) muscle force; to determine the agreement among the equations in identifying QF muscle weakness in COPD patients; and to assess the differences in characteristics among the groups of patients classified as having or not having QF muscle weakness by each equation.Methods: Fifty-six COPD patients underwent assessment of peak QF muscle force by dynamometry (maximal voluntary isometric contraction of knee extension). Predicted values were calculated with three equations: an age-height-weight-gender equation (Eq-AHWG); an age-weight-gender equation (Eq-AWG); and an age-fat-free mass-gender equation (Eq-AFFMG).Results: Comparison of the percentage of predicted values obtained with the three equations showed that the Eq-AHWG gave higher values than did the Eq-AWG and Eq-AFFMG, with no difference between the last two. The Eq-AHWG showed moderate agreement with the Eq-AWG and Eq-AFFMG, whereas the last two also showed moderate, albeit lower, agreement with each other. In the sample as a whole, QF muscle weakness (< 80% of predicted) was identified by the Eq-AHWG, Eq-AWG, and Eq-AFFMG in 59%, 68%, and 70% of the patients, respectively (p > 0.05). Age, fat-free mass, and body mass index are characteristics that differentiate between patients with and without QF muscle weakness.Conclusions: The three equations were statistically equivalent in classifying COPD patients as having or not having QF muscle weakness. However, the Eq-AHWG gave higher peak force values than did the Eq-AWG and the Eq-AFFMG, as well as showing greater agreement with the other equations.


ResumoObjetivo:Comparar diferentes fórmulas de predição do pico de força muscular do quadríceps femoral (QF); investigar a concordância entre elas para identificar fraqueza muscular de QF em pacientes com DPOC; e verificar as diferenças nas características nos grupos de pacientes classificados com presença ou ausência dessa fraqueza de acordo com cada fórmula.Métodos: Cinquenta e seis pacientes com DPOC foram avaliados quanto ao pico de força muscular do QF por dinamometria (contração isométrica voluntária máxima de extensão de joelho). Os valores preditos foram calculados com três fórmulas: uma fórmula composta por idade-altura-peso-gênero (F-IAPG); uma por idade-peso-gênero (F-IPG); e uma por idade-massa magra-gênero (F-IMMG).Resultados: A comparação da porcentagem do predito obtida pelas fórmulas mostrou a F-IAPG com maiores valores do que os valores de F-IPG e F-IMMG, sem diferença entre as duas últimas. A F-IAPG apresentou concordância moderada com F-IPG e F-IMMG, enquanto essas últimas também apresentaram concordância moderada, mas menor, entre si. Do total de pacientes, a fraqueza muscular de QF (< 80% do predito) foi identificada por F-IAPG, F-IPG e F-IMMG em 59%, 68% e 70% dos pacientes, respectivamente (p > 0,05). Idade, massa magra e índice de massa corpórea são características que diferenciam pacientes com e sem fraqueza muscular de QF.Conclusões: As três fórmulas foram estatisticamente equivalentes para classificar pacientes com DPOC como portadores ou não de fraqueza muscular de QF. Entretanto, a F-IAPG apresentou maiores valores de pico de força do que F-IPG e F-IMMG, assim como maior concordância com as outras fórmulas.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Algorithms , Muscle Strength/physiology , Muscle Weakness/diagnosis , Pulmonary Disease, Chronic Obstructive/physiopathology , Quadriceps Muscle/physiopathology , Adiposity , Age Factors , Body Height , Body Mass Index , Body Weight , Cross-Sectional Studies , Health Services Needs and Demand , Isometric Contraction/physiology , Knee/physiopathology , Muscle Strength Dynamometer/trends , Predictive Value of Tests , Respiratory Function Tests , Sex Factors
8.
Fisioter. pesqui ; 20(1): 2-10, mar. 2013. ilus, tab
Article in Portuguese | LILACS | ID: lil-674293

ABSTRACT

O objetivo do estudo foi analisar a influência do calçado de salto alto na atividade eletromiográfica (EMG) do músculo quadríceps durante a tarefa de sentar e levantar. Participaram deste estudo 10 voluntárias assintomáticas com 20,2±3,0 anos e 10 voluntárias com síndrome da dor femoropatelar (SDFP) com 21,3±3,4 anos. As voluntárias executaram a tarefa de sentar e levantar em 3 diferentes condições: descalças, com tênis e com calçado de salto de 10 cm. A atividade EMG do vasto medial oblíquo (VMO), vasto lateral (VL) e reto femoral (RF) foi registrada durante a execução das tarefas por meio de eletrodos de superfície simples diferencial conectados ao eletromiógrafo. Para comparação entre grupos e tarefas, foi utilizado o teste ANOVA com medidas repetidas e o post hoc do teste de Tukey (p<0,05). Os resultados demonstraram maior atividade EMG do músculo VMO, no grupo Controle, durante as tarefas de levantar e sentar utilizando o salto alto. No grupo SDFP, foi observado aumento da atividade EMG do VL na tarefa de levantar do banco e diminuição da razão VMO:VL com o uso do salto alto. Os resultados mostraram que o uso do salto alto pode provocar um aumento da atividade do VL em relação ao VMO em mulheres com SDFP, fato esse que pode colaborar para o mau alinhamento patelar e agravamento da SDFP. Portanto, os resultados sugerem que esse tipo de calçado deve ser evitado por mulheres com SDFP.


The purpose of this study was to analyze the influence of high-heeled shoes on the quadriceps electromyographic activity (EMG) during the sit-to-stand task. Ten healthy females (20.2±3.0 years) and 10 females with patellofemoral pain syndrome (PFPS) (21.3±3.4 years) participated in this study. The subjects performed a standardized sit-to-stand task under 3 conditions: barefoot, wearing sneakers and wearing 10 cm high-heeled shoes. The electromyographic (EMG) activity was recorded from the vastus medialis obliquus (VMO), vastus lateralis (VL) and rectus femoris (RF) muscles during the tasks using simple differential surface electrodes connected to an EMG system. To compare data between groups and tasks, the ANOVA test with repeated measures and the Tukey post hoc test were applied (p<0.05). Results demonstrated higher EMG activity for the VMO muscles during stand and sit tasks performed with high-heeled shoes in the control group. In the PFPS group, an increased EMG activity for the VL muscle during the stand task was observed, and the VMO:VL ratio decreased with the use of high heels. Results show that the use of high-heeled shoes can further increase the EMG activity of the VL muscle than the VMO in women with PFPS, a fact that may contribute to the increased joint imbalance and worsened PFPS. Therefore, the results suggest that this type of footwear should be avoided by women with PFPS.


El objetivo del estudio fue analizar la influencia del calzado de tacón alto en la actividad electromiográfica (EMG) del músculo cuadríceps durante la tarea de sentarse y levantarse. Participaron de este estudio 10 voluntarias asintomáticas con 20,2±3,0 años y 10 voluntarias con síndrome de dolor patelofemoral (SDPF) con 21,3±3,4 años. Las voluntarias ejecutaron la tarea de sentarse y levantarse en tres diferentes condiciones: descalzas, con zapatillas y con calzado de tacón de diez centímetros. La actividad EMG del vasto medial oblícuo (VMO), vasto lateral (VL) y recto femoral (RF) fue registrada durante la ejecución de las tareas por medio de electrodos de superficie diferenciales conectados al electromiógrafo. Para la comparación entre grupos y tareas fue utilizada la prueba ANOVA con medidas repetidas y post test de Tukey (p<0,05). Los resultados demostraron más actividad EMG del músculo VMO, en el grupo Control durante las tareas de levantarse y sentarse utilizando el tacón alto. En el grupo SDPF fue observado un aumento de la actividad EMG del VL en la tarea levantarse del banco y disminución de la relación VMO:VL con el uso de tacón alto. Los resultados mostraron que el uso de tacón alto puede causar un aumento de la actividad del VL en relación al VMO en mujeres con SDPF, un hecho que puede colaborar para un mal alineamiento patelar y una agravación del SDPF. Por lo tanto, los resultados sugieren que ese tipo de calzado debe ser evitado por mujeres con SDFP.


Subject(s)
Humans , Female , Knee Joint/physiopathology , Electromyography , Quadriceps Muscle/physiopathology , Patellofemoral Pain Syndrome , Shoes/adverse effects , Knee Injuries/pathology
9.
Rev. bras. ortop ; 48(1): 111-113, Jan-Feb/2013. graf
Article in English | LILACS | ID: lil-674579

ABSTRACT

The total rupture of the quadriceps muscle in an adolescent is a rare lesion. We report a case of a 13 year old boy who suffered a direct trauma to the left knee. No predisposing factors have been diagnosed. The lesion was treated with surgical repair and transosseus sutures. The aim of this study was to present a rare case of rupture of the quadriceps muscle in an adolescent and the therapy used.


A ruptura total do músculo quadríceps em um adolescente é uma lesão rara. Nós relatamos um caso de um menino de 13 anos que sofreu um trauma direto no joelho esquerdo. Não foram diagnosticados fatores predisponentes. A lesão foi tratada com o reparo cirúrgico e suturas transósseas. O objetivo desta pesquisa foi apresentar um caso raro de ruptura do músculo quadríceps em um adolescente e a terapêutica adotada.


Subject(s)
Humans , Male , Adolescent , Quadriceps Muscle/physiopathology , Quadriceps Muscle/injuries , Rupture
10.
Braz. j. phys. ther. (Impr.) ; 16(2): 148-156, mar.-abr. 2012. ilus
Article in English | LILACS | ID: lil-624724

ABSTRACT

BACKGROUND: Reductions in quadriceps strength and peak aerobic capacity (VO2) in patients with chronic obstructive pulmonary disease (COPD) have been studied in relatively small samples over a short period. Moreover, results were not corrected for confounding variables, such as lean muscle mass, gender, and gas transfer capacity of the lungs. OBJECTIVES: To compare quadriceps muscle strength and peak V.O2 in women and men while stratifying for age and gas transfer capacity. We then corrected for lower-limb lean muscle mass to see whether and to what extent the age-graded reduction remained evident. METHODS: Retrospectively, data of 374 women and 593 men with COPD were analyzed: lung function, current drug therapy, quadriceps strength, peak V.O2, lower-limb lean muscle mass, and gas transfer capacity. RESULTS: Quadriceps strength and peak V.O2 were lower in older women and men with a gas transfer capacity of <50% predicted, also after adjustment for lower-limb lean muscle mass. Moreover, quadriceps strength and peak V.O2 were lower in older women and men with a gas transfer capacity of <50% predicted, also after adjustment for lower-limb lean muscle mass. Moreover, quadriceps strength and peak V.O2 were related to age in COPD, particularly in women and men with a gas transfer capacity of >50% predicted. Yet, counter to our hypothesis, lower-limb lean muscle mass did not show an age-graded reduction and, in turn, could not account for the relationship of age with quadriceps strength and peak V.O2. CONCLUSIONS: It is apparent that there is an age-graded reduction in skeletal muscle function in patients with COPD. Therefore, prevention of an age-graded decline in quadriceps muscle strength and peak V.O2 may need to become an outcome of pulmonary rehabilitation of patients with COPD.


CONTEXTUALIZAÇÃO: As reduções da força do quadríceps e do pico de consumo de oxigênio (V.O2) em pacientes com doença pulmonar obstrutiva crônica (DPOC) são estudadas em amostras relativamente pequenas e por curto período de tempo. Além disso, os resultados não são corrigidos por variáveis confundidoras, como conteúdo de massa magra, gênero e capacidade de difusão pulmonar. OBJETIVOS: Comparar a força muscular do quadríceps e o pico de V.O2 em mulheres e homens estratificados por idade e capacidade de difusão pulmonar e, então, corrigir pela massa magra dos membros inferiores para verificar se e até que ponto a redução graduada por idade permaneceu evidente. MÉTODOS: Retrospectivamente, foram analisados dados de 374 mulheres e 593 homens com DPOC, referentes a: função pulmonar, tratamento medicamentoso, força do quadríceps, pico de V.O2, massa magra dos membros inferiores e capacidade de difusão pulmonar. RESULTADOS: A força muscular do quadríceps e o pico de V.O2 foram menores em idosos com capacidade de difusão pulmonar <50% do previsto, mesmo após correção pela massa magra dos membros inferiores. Além disso, a força do quadríceps e o pico de V.O2 correlacionaram-se com a idade, especialmente em homens e mulheres com capacidade de difusão >50% do previsto. No entanto, a massa magra dos membros inferiores não demonstrou redução graduada por idade e não justificou a relação da idade com a força do quadríceps e o pico de V.O2, contrariando a nossa hipótese. CONCLUSÕES: Aparentemente, há uma redução graduada por idade na função musculoesquelética em pacientes com DPOC. Portanto, a prevenção do declínio graduado por idade na força do quadríceps e no pico de V.O2 deveria ser um objetivo da reabilitação pulmonar em pacientes com DPOC.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Exercise Tolerance , Muscle Strength , Pulmonary Disease, Chronic Obstructive/physiopathology , Quadriceps Muscle/physiopathology , Age Factors , Retrospective Studies , Sex Factors
11.
Arq. bras. endocrinol. metab ; 56(2): 128-136, Mar. 2012. tab
Article in English | LILACS | ID: lil-622533

ABSTRACT

OBJECTIVES: To evaluate the impact of subclinical hypothyroidism (sHT) treatment on health-related quality of life (QoL), psychiatric symptoms, clinical score, and muscle function. MATERIALS AND METHODS: In this randomized double-blind study, patients were assigned either to treatment (n = 35) or placebo (n = 36). Clinical and psychiatric symptoms were assessed by the Zulewski, Hamilton and Beck scales. QoL was assessed by the SF-36 questionnaire. Assessments of quadriceps (QS) and inspiratory muscle (IS) strength were performed by a chair dynamometer and a manuvacuometer. RESULTS: Treatment improved IS (+11.5 ± 17.2; p = 0.041), as did QoL domains "Pain" and "Role Physical" (+19.7 ± 15.2, 0.039 and +22.1 ± 47.5, p = 0.054; respectively). Clinical and psychiatric symptoms showed similar responses to both interventions. CONCLUSIONS: sHT treatment improved IS and physical aspects of QoL, despite no impact in other muscle parameters. Clinical score, psychiatric symptoms, and SF-36 domains, based on mental dimensions of QoL may be more susceptible to "placebo effect" in patients with sHT.


OBJETIVOS: Avaliar o impacto do tratamento do hipotireoidismo subclínico (sHT) na qualidade de vida relacionada à saúde (QoL), aos sintomas psiquiátricos, ao escore clínico e à função muscular. MATERIAIS E MÉTODOS: Em um ensaio randomizado duplo-cego, pacientes foram randomizados para tratamento (n = 35) ou uso de placebo (n = 36). Sintomas clínicos e psiquiátricos foram acessados por meio das escalas de Zulewski, Hamilton e Beck. A QoL foi avaliada pelo questionário SF-36. Medidas da força de quadríceps (QS) e inspiratória (IS) foram obtidas por um dinamômetro de cadeira e um manovacuômetro. RESULTADOS: O tratamento melhorou a IS (+11,5 ± 17,2; p = 0,041), assim como os domínios "Dor" e "Aspectos Físicos" da QoL (+19,7 ± 15,2, 0,039 e +22,1 ± 47,5, p = 0,054, respectivamente). Sintomas clínicos e psiquiátricos demonstraram respostas similares a ambas as formas de intervenção. CONCLUSÕES: Tratamento do sHT melhorou IS e aspectos físicos da QoL, apesar de não ter impacto em outros parâmetros musculares. Escore clínico, sintomas psiquiátricos e domínios do SF-36 que focam em dimensões mentais podem ser mais suscetíveis ao "efeito placebo" em pacientes com sHT.


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Hormone Replacement Therapy/adverse effects , Hypothyroidism/psychology , Muscle Strength/drug effects , Quality of Life , Thyroxine/therapeutic use , Double-Blind Method , Hypothyroidism/drug therapy , Hypothyroidism/physiopathology , Placebo Effect , Pain/physiopathology , Quadriceps Muscle/drug effects , Quadriceps Muscle/physiopathology , Respiratory Muscles/drug effects , Respiratory Muscles/physiopathology
12.
Clinics ; 62(2): 127-132, Apr. 2007. tab
Article in English | LILACS | ID: lil-449651

ABSTRACT

PURPOSE: To evaluate torque and the hamstring/quadriceps ratio of the knee of athletes with and without anterior cruciate ligament laxity. METHODS: Twenty-eight male athletes, 19 without anterior cruciate ligament laxity and 9 with anterior cruciate ligament laxity, were evaluated with an isokinetic machine model Cybex 770. The peak torque of quadriceps and hamstrings was compared, and the hamstring/quadriceps ratio on the constant angular speed of 60° per second were also compared. RESULTS: In athletes with anterior cruciate ligament laxity, the peak torque values (right and left knees) of flexors (120 ± 15 and 116 ± 15 Nm) and of extensors (218 ± 36 Nm and 207 ± 26 Nm) were not different than those of athletes without laxity (109 ± 21 Nm and 111 ± 22 Nm; 191 ± 5 Nm and 188 ± 35 Nm). The hamstring/quadriceps ratio of athletes with laxity (right: 57 ± 6 percent and left: 56 ± 8 percent) did not differ from those without anterior cruciate ligament laxity (right: 58 ± 9 percent and left: 58 ± 7 percent). CONCLUSIONS: The anterior cruciate ligament laxity of long distances running athletes did not significantly alter the peak torque of flexors and of extensors or the hamstring/quadriceps ratio.


OBJETIVO: Avaliar o torque e a relação de forças entre ísquios-tibiais/quadríceps dos joelhos de atletas corredores de longas distâncias com e sem frouxidão do ligamento cruzado anterior. METODOLOGIA: Vinte e oito atletas do gênero masculino, 19 sem frouxidão do ligamento cruzado anterior e 9 com frouxidão do ligamento cruzado anterior foram avaliados com aparelho isocinético modelo Cybex 770. Comparou-se o pico de torque dos quadríceps e dos ísquios-tibiais e a relação ísquios-tibiais/quadríceps na velocidade angular constante de 60° por segundo. Os dados obtidos foram comparados por meio dos testes t de Student e para dados pareados (membros direito e esquerdo) e o nível de significância estabelecido foi p < 0,05. RESULTADOS: Nos atletas com frouxidão do ligamento cruzado anterior os valores de pico de torque (joelhos direito e esquerdo) dos flexores (120 ± 15 Nm e 116 ± 15 Nm) e dos extensores (218 ± 36 Nm e 207 ± 26 Nm) não diferiram significantemente dos atletas sem frouxidão (109 ± 21 Nm e 111 ± 22 Nm; 191 ± 5 Nm e 188 ± 35 Nm). A relação ísquios-tibiais/quadríceps dos atletas com frouxidão (57 ± 6 por cento e 56 ± 8 por cento) também não diferiu daqueles sem frouxidão do ligamento cruzado anterior (58 ± 9 por cento e 58 ± 7 por cento). CONCLUSÕES: A frouxidão do ligamento cruzado anterior não alterou significantemente o pico de torque dos flexores e extensores e a relação ísquios-tibiais/quadríceps dos joelhos de atletas corredores de longas distâncias.


Subject(s)
Adult , Humans , Male , Anterior Cruciate Ligament/physiopathology , Isometric Contraction/physiology , Joint Instability/physiopathology , Muscle Strength/physiology , Running/physiology , Anterior Cruciate Ligament/injuries , Joint Instability/diagnosis , Physical Endurance/physiology , Quadriceps Muscle/injuries , Quadriceps Muscle/physiopathology , Running/injuries , Torque
SELECTION OF CITATIONS
SEARCH DETAIL